Banca de DEFESA: TIAGO NOVAIS ROCHA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : TIAGO NOVAIS ROCHA
DATE: 14/08/2020
TIME: 14:00
LOCAL: Videoconferência
TITLE:

THE ROLE OF MULTIPARITY AND MATERNAL AGE AT FIRST PREGNANCY IN THE ASSOCIATION BETWEEN EARLY MENARCHE AND METABOLIC SYNDROME AMONG MIDDLE-AGED AND OLDER WOMEN

KEY WORDS:

Menarche. Women. Risk factors. Metabolic syndrome. Pregnancy.

PAGES: 81
BIG AREA: Ciências da Saúde
AREA: Fisioterapia e Terapia Ocupacional
SUMMARY:

Introduction: Metabolic syndrome (MetS) is a common condition in older ages, however, it is known that it is associated with factors present in the early stages of life, such as early menarche. Other factors such as age at first pregnancy and parity are also associated with increased cardiovascular risk in women, but their role in the association between early menarche and MetS has not yet been studied. Objective: To analyze an association between early menarche and MetS in middle-aged women, and to verify whether the maternal age at first pregnancy and the parity to use as mediating variables. Methods: This is an observational, analytical, cross-sectional study, composed of 428 women aged between 40 and 80 years. The age at first pregnancy, parity and early menarche (≤ 11 years of age) were assessed by self-report, and an MetS was assessed using the tests recommended by the NCEP ATP III (Systemic arterial hypertension, high triglycerides, high HDL, high fasting blood glucose and waist circumference> 88 cm). The association MetS and early menarche were assessed by binary logistic regression analysis adjusted for the covariables age, smoking, family income, education and physical exercise. The role of age at first pregnancy and multiparity on an early menarche and MS relationship were assessed through mediation analysis adjusted by the same covariables. Results: There was an association between early menarche and MetS (OR: 2,262 CI: 1,145; 4,465) altering early menarche twice increases the chance of a woman exhibiting MetS in future ages. Through mediation analysis it was possible to verify that menarche has a direct effect on MetS (Effect: 0,8076 CI: 0,1070; 1.5082), and two potential mediators, only the maternal age at first pregnancy was a significant path (Effect: 0,0654 CI: 0,0035; 0,2205). Conclusion: The results of this research show that there is an association between early menarche and MetS and that maternal age at first pregnancy is registered as a mediating variable in this association In this sense, bear in mind that pregnancy at a younger age tends to affect women's health more negatively when compared to pregnancy in adulthood, health strategies aimed at the female adolescent population should be carried out in order to lessen the effects of pregnancy on adolescence, as well as its prevention, as they would act positively in the non-development of MetS in future ages.

BANKING MEMBERS:
Presidente - 3885543 - SAIONARA MARIA AIRES DA CAMARA
Externo ao Programa - 1674532 - DIMITRI TAURINO GUEDES
Externa à Instituição - MAYLE ANDRADE MOREIRA - UFC