Transcranial direct current stimulation, Diabetes, Diabetic neuropathies
Introduction: Diabetes mellitus is a disease with high prevalence worldwide, especially in Brazil, where 16% of patients are affected by diabetic polyneuropathy and all current treatments have not shown good long-term efficacy. Transcranial direct current stimulation (tDCS) is a technique that promotes brain neuromodulation, inducing changes in the excitability of the human cortex. tDCS promotes physiological effects that extend to physical and behavioral aspects. Thus, it may be a potential treatment for pain in diabetic polyneuropathy. Objective: The primary aim of this study is to analyze the effects of tDCS on pain in patients with diabetic polyneuropathy. Methods: A randomized controlled, double-blind, 2-arm clinical trial will be carried out from March to July 2022 at the Onofre Lopes University Hospital, in Natal, RN. Individuals of both sexes aged between 30 to 69 years will be enrolled, with a total of 30 participants divided into two groups. Pain, functionality, quality of life, muscle strength and sleep will be evaluated. Expected results: We expect the improvement of the variables studied and new evidence of treatment for this population. We suggest that tDCS can be used as an alternative method for the treatment of diabetic polyneuropathy.