Banca de QUALIFICAÇÃO: ABRAÃO SÉRVULO DO NASCIMENTO
Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.STUDENT : ABRAÃO SÉRVULO DO NASCIMENTO
DATE: 06/12/2021
TIME: 14:00
LOCAL: Por parecer
TITLE:
EFFECTIVENESS OF TRANSCRANIAL DIRECT CURRENT STIMULATION ON PAIN AND FUNCTIONALITY IN CHRONIC CHIKUNGUNYA ARTHRALGIA: A STUDY PROTOCOL FOR A RANDOMIZED CLINICAL TRIAL
KEY WORDS:
Transcranial Direct Current Stimulation, arbovirus infections, arthritis.
PAGES: 24
BIG AREA: Ciências da Saúde
AREA: Fisioterapia e Terapia Ocupacional
SUMMARY:
Introduction: The chikungunya virus infection is still an epidemic in Brazil with an incidence of 59.4 cases per 100,000 in the Northeast region. More than 60% of the patients present relapsing and remitting chronic arthralgia with debilitating pain lasting for years. There are no specific therapeutic agents to treat and rehabilitate persons with chikungunya. Persistent pain can lead to incapacitation, requiring long-term pharmacological treatment. Transcranial direct current stimulation (tDCS) appears promising as a novel neuromodulation approach for pain-related networks to alleviate pain in several chronic pain syndromes.
Methods and analysis: In this study, we hypothesize that anodal motor cortex tDCS (C3/Fp2 montage) will improve pain and functionality in patients with chronic chikungunya arthralgia. We describe the protocol of a single-center, parallel-design, double-blind, randomized, sham-controlled trial. Forty participants with chronic chikungunya will be randomized to either an active or a sham tDCS group. A total of 10 sessions lasting 20 min each will be administered over 2 weeks (one per weekday) using a monophasic continuous current with an intensity of 2 mA for 20 min. Participants in both groups will be evaluated at baseline, immediately after the 10th session, 2 weeks (first follow-up), and 4 weeks (second follow-up) after the intervention. Primary outcome: pain assessed using numeric rating scale and algometry. Secondary outcomes: muscle strength, functionality, and quality of life. The effects of stimulation will be calculated using a mixed analysis of variance (ANOVA) model.
Ethics and dissemination: The study was approved by the ethics committee of the Faculty of Health Sciences of Trairí – Federal University of Rio Grande do Norte (UFRN) (No. 2.413.851) and registered in the Brazilian Registry of Clinical Trials (ReBEC) under the identifier RBR-469YD6. Study results will be disseminated through presentations at conferences and publications in peer-reviewed journals.
BANKING MEMBERS:
Presidente - 2646619 - RODRIGO PEGADO DE ABREU FREITAS
Interno - 4964489 - CLECIO GABRIEL DE SOUZA
Externo ao Programa - 2917953 - ARTUR QUINTILIANO BEZERRA DA SILVA