Banca de DEFESA: KARIME ANDRADE MESCOUTO

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : KARIME ANDRADE MESCOUTO
DATA : 25/07/2018
HORA: 09:00
LOCAL: HUAB
TÍTULO:

EFFECTS OF TRANSCRANIAL DIRECT CURRENT STIMULATION ON PHYSICAL AND BEHAVIORAL VARIABLES IN WOMEN WITH FIBROMYALGIA - A RANDOMIZED CONTROLLED CLINICAL TRIAL

PALAVRAS-CHAVES:

 Chronic Pain. Transcranial Direct Current Stimulation. Rehabilitation

PÁGINAS: 80
GRANDE ÁREA: Ciências da Saúde
ÁREA: Fisioterapia e Terapia Ocupacional
RESUMO:

Background: Fibromyalgia (FM) is a syndrome characterized by chronic
widespread pain, fatigue, cognitive behavioral impairments, mood disorders
and sleep problems. Although the etiology of FM is unknown, it has been
recognized as a centralized pain state where the patient’s Central Nervous
System (CNS) is hyperactive, phenomenon known by Central Sensitization.
Transcranial Direct Current Stimulation (tDCS) is a non-invasive, safe and
cost-effective brain stimulation technique that modulates cortical excitability
and has been showing positive effects in FM patients. However, there is no
consensus on which method and exactly location of stimulation is most
effective and presents with more significant benefits in this patients
population. Objective: The aim of this study is to evaluate whether a 5
consecutive day treatment with tDCS stimulation results in better pain levels
when compared to sham, or placebo, and if there are any differential effect
between active tDCS and sham tDCS on pressure pain threshold, pressure
pain tolerance, mood disorders such as anxiety, depression and affectivity
and the disease functional impact in women with FM. Methods: This
randomized controlled trial had forty-five participants with FM, which were
randomized in one of three groups: active tDCS in the primary motor cortex
(M1; n=15) and dorsolateral prefrontal cortex (DLPFC; n=15) and sham
stimulation (SHAM; n=15). All the data were collected 7 days prior to the
begging of the intervention (baseline), on the 5 th day of treatment, with 7 and
21 days of follow-up. The pressure pain threshold and tolerance were also
revaluated at the 1 st day of treatment to analyze the immediate effect of tDCS.
A constant current of 2 mA intensity was administered during 5 consecutive
days for 20min. Results: The results showed there was no statistical
significant improvement in pain in any of the groups (p > 0,05). However,
there was a reduction of 15,1% of the disease functional impact in M1 (p =
0,003) and 8,7% in DLPFC (p = 0,022) resulting in improved function of this
patient population. In addition, the results showed an improvement in anxiety
levels in DLPFC group (p < 0,05) with effects maintenance of up to follow-up
periods. There was no statistical difference on the other variables.
Conclusion: The results of this study suggests that tDCS treatment of 5
consecutive days in cortical areas M1 and DLPFC of 2mA intensity for 20min
have significant results in function and anxiety in patients with FM with
sustained effects after treatment ended.

MEMBROS DA BANCA:
Presidente - 2646619 - RODRIGO PEGADO DE ABREU FREITAS
Interno - 2275864 - CAIO ALANO DE ALMEIDA LINS
Externo à Instituição - FUAD AHMAD HAZIME - UFPI